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Healthspan Vein Vine 360mg (90 Tablets) | for Tired & Heavy Legs | Maintains Healthy Leg-Vein Functions | Red Vine Leaf Extract | Added Vitamins B1 & C | Vegan

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Recent studies have investigated the action of flavonoids in preventing atherosclerotic plaques (Hollman and Katan, 1997). Bioflavonoids or flavonoids are a class of water-soluble substances found in a number of plants or plant-derived products. It is believed that flavonoids have a wide range of beneficial effects when taken in the diet, including anti-inflammatory, antihistaminic and antiviral action. Formica and Regelson (1995) concluded that flavonoids are important in the maintenance of capillary wall integrity and resistance. These studies appear to have been well designed -while the numbers involved were small, the results achieved statistical significance and good control systems were used. Further studies will be required to assess whether or not red vine leaf extract AS 195 can achieve improvements in microvascular bloodflow in patients with other microvascular diseases such as diabetes. A cooling leg gel containing red vine leaf extracts that is designed to soothe and refresh tired, heavy legs, is also available. Holland & Barrett Leg Vein Formula is carefully developed to help maintain healthy circulation in the legs. The capsules contain Red Vine leaf extract which contributes to good blood flow in the legs, along with grapeseed extract and Vitamin C.

If the leg vein valves collapse, then swollen veins become distended and tortuous and may bulge beneath the skin to form varicose veins. Numerous studies report that the antioxidants in red vine leaves and the subsequent red vine leaf extract are efficient for the treatment of varicose veins, also known as chronic venous insufficiency. The extract has successfully been used in clinical trials to prevent edema (swelling) and other symptoms associated with the condition. Following a 42-day study, subjects reported an improvement in symptoms such as: tiredness and fatigue, pain, tingling and tension sensation in the legs ( Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial). Drug therapy is a treatment option in incipient and mild to moderate CVI. Leach’s (2004) review of leg ulceration included the evidence for systemic therapy, namely orally administered phlebotonic (venotonic) agents. Such drugs are often plant-derived substances for which an anti-exudative (anti-inflammatory) and anti-oedematous action and efficacy have been confirmed in experimental studies and clinical trials. Experimentally, most have a membrane-stabilising action, leading to a decrease in capillary permeability. Some also have antioxidant properties. Red Vine Leaf Extract (AS 195) Can Improve Some Signs and Symptoms of Chronic Venous Insufficiency, a Systematic Review

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Martyn Butcher, RGN, Dip HSW, CertMHS tissue viability clinical nurse specialist, Plymouth Hospitals NHS Trust, Plymouth

Eladiet offers us Red Vine in tablets, a supplement that helps maintain normal circulation. In herbal medicine, the red vine is known primarily for its benefits on the bloodstream. Kiesewetter, H. et al (2000) Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II). Arzneimittelforschung; 50: 2, 109-117. Of course, the aesthetics industry is already full of myths, inaccuracies, platitudes and hallucinations anyway, so the advent of AI does not make much of a difference. The beauty industry has always been full of BS, AI or no AI. Although the red vine leaf extract studies were small in number, the available evidence suggests that AS 195 has properties that may help to maintain healthy leg-vein function. As such, its role in the prevention of CVI and in ameliorating established venous disease could be further explored. Such investigations may include evaluation of the correction of early vein changes to prevent venous ulceration and the role of red vine leaf extract in maintaining leg-vein integrity, thus leading to enhanced treatment options and a recurrence-prevention strategy. The usual dose is 360 mg to 720 mg daily, but follow manufacturer’s instructions as the concentration of red vine leaf extracts vary. Only select supplements made to a pharmaceutical standard known as GMP, as low quality red vine leaf products (on sale in health food shops in Japan) were found to contain low levels of active polyphenols, and inconsistent levels per tablet.The placebo group demonstrated an increase in lower leg volume at six weeks and at 12 weeks. Patients treated with red vine leaf extract AS 195 showed a decrease in mean volume compared with the control group. The results of changes in ankle circumference were similarly positive, with reductions in the active treatment groups but little change in the placebo group. All patients in the active treatment groups had subjective improvements in symptoms at six weeks, and the changes were significantly greater after 12 weeks. The researchers concluded that adding angioprotectors ( red vine leaf extract) to standard medical treatment helps to correct endothelial dysfunction (the ability of veins to recover and dilate) and may improve the immediate results for patients with acute venous thrombosis. Red vine leaf dose Red vine leaf extracts stabilise the endothelial lining of tiny capillaries and promote their repair and reduce their permeability. This makes capillaries less leaky so less fluid passes from the circulation into the tissues to cause swelling of (oedema) of surrounding tissues. Our red vine leaves are harvested when its nutrient content is at its highest; the leaves are then dried and its nutrients extracted using precise temperature controls and purified water, guaranteeing a grapevine extract of the highest quality. Each tablet contains 360mg of natural red vine leaf extract - equivalent to 5,400mg of fresh red vine leaf - including 40% polyphenols, the key ingredient. Take daily for at least six weeks to start seeing the full benefits.

In contrast, in France, Germany and Italy these natural extracts have been widely researched and used for decades, either as nutritional supplements or even actual medicines and are very popular with women suffering from CVI, water retention and cellulite. The available red vine leaf extracts available today for use in cosmetics are not concentrated enough in active molecules for use in cellulite creams.Grapes are incredibly succulent and flavorful fruits. However, grape leaves have a sort of bland, leafy green, almost dry flavor with a slight, barely noticeable bitter aftertaste when cooked. How to use grape vine leaves in the kitchen Out of the 56 studies assessed in the trial, 5 clinical trials were selected according to the strictest inclusion criteria. A source of flavonoids that has undergone extensive preclinical and clinical investigation is the red vine leaf extract AS 195. This has shown that its flavonoids may have significant benefits for patients with pre-ulcer venous hypertension. Red vine leaf extract AS 195

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